2-Methyl-2-propanyl [(1R)-1-cyanoethyl]carbamate(CAS: 100927-09-1)

2-Methyl-2-propanyl [(1R)-1-cyanoethyl]carbamate is a white crystalline solid with a molecular weight of approximately 156.18 g/mol. It has a solubility of about 7.4 g/100 mL in water and is slightly soluble in common organic solvents such as ethanol and acetone. It is mildly reactive and can undergo hydrolysis under basic conditions.

2-Methyl-2-propanyl [(1R)-1-cyanoethyl]carbamate is typically synthesized via a condensation reaction between 2-methylpropanoyl chloride and 1-cyanoethylamine hydrochloride in the presence of a catalytic amount of pyridine. This process yields a pure product with a high selectivity and good yield.

2-Methyl-2-propanyl [(1R)-1-cyanoethyl]carbamate is used in pharmaceuticals for synthesizing certain active pharmaceutical ingredients. It also finds applications in the polymer and sensor industries for specific reagent and functional material preparation.

When handling 2-Methyl-2-propanyl [(1R)-1-cyanoethyl]carbamate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled with caution, and the Material Safety Data Sheet (MSDS) should be referenced for specific spill cleanup procedures.