2-Hydroxy-N-methylbenzamide(CAS: 1862-88-0)

2-Hydroxy-N-methylbenzamide (CAS: 1862-88-0) is a white crystalline solid with a molecular weight of approximately 183.21 g/mol. Its solubility in water is about 1.5 g/100 mL at 20°C. Chemically, it is slightly basic and exhibits moderate reactivity in esterification and amide bond formation reactions.

2-Hydroxy-N-methylbenzamide is typically synthesized by reacting salicylaldehyde with methylamine in the presence of a base such as sodium hydroxide. The reaction is carried out under reflux until completion, followed by acidification and recrystallization to purify the product. Yields are generally around 80-85% with good selectivity.

2-Hydroxy-N-methylbenzamide (CAS: 1862-88-0) is used in various industries, including pharmaceuticals for its role as an intermediate in drug synthesis, polymers for its stabilizing properties, and as a component in sensors and semiconductors due to its electronic properties.

When handling 2-Hydroxy-N-methylbenzamide (CAS: 1862-88-0), it is important to use appropriate personal protective equipment (PPE) such as gloves and eye protection. It should be stored in a well-ventilated area away from heat and open flames. In case of a spill, use appropriate tools to contain and clean up the material, and refer to the Safety Data Sheet (SDS) for detailed instructions.