1-(4-Bromo-2,6-difluorophenyl)methanamine(CAS: 887585-99-1)

1-(4-Bromo-2,6-difluorophenyl)methanamine is a solid with a crystalline form. Its molecular weight is approximately 281.03 g/mol. It has a low water solubility but is soluble in organic solvents like ethanol and acetone. This compound is reactive and can undergo electrophilic aromatic substitution reactions and nucleophilic aminolysis.

1-(4-Bromo-2,6-difluorophenyl)methanamine is typically synthesized via a multi-step process involving the bromination of a 2,6-difluorophenyl group, followed by the substitution of a methylamine. This can be achieved using reagents like N-bromosuccinimide (NBS) and a radical initiator, yielding a high yield of the desired product with good selectivity.

1-(4-Bromo-2,6-difluorophenyl)methanamine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also utilized in polymer science for the modification of polymers and in the development of sensors and semiconductors due to its unique chemical properties.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential when handling 1-(4-Bromo-2,6-difluorophenyl)methanamine. It should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed emergency response procedures.