5-Bromonicotinonitrile(CAS: 35590-37-5)

5-Bromonicotinonitrile (CAS: 35590-37-5) has a crystalline form with a molecular weight of approximately 178.01 g/mol. It has a high solubility in polar organic solvents like acetone and methanol. Chemically, it is moderately reactive, particularly when exposed to strong bases or reducing agents. It is less soluble in water, making it suitable for applications where aqueous solubility is not a requirement.

5-Bromonicotinonitrile (CAS: 35590-37-5) is commonly synthesized via the reaction of nicotinonitrile with bromine in the presence of a solvent such as acetic acid. The reaction is carried out under mild conditions, typically at room temperature, with high yield and good selectivity. Common solvents used include acetic acid and acetonitrile, with acetic acid being the more preferred choice.

5-Bromonicotinonitrile (CAS: 35590-37-5) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the chemical industry for the development of polymers and as a precursor in the manufacture of electronic materials. Its use in sensors and semiconductors is limited but growing due to its unique chemical properties.

Handling 5-Bromonicotinonitrile (CAS: 35590-37-5) requires appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be performed in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate materials, and waste should be disposed of in accordance with local regulations. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.