1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol(CAS: 147591-46-6)

1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol is a crystalline compound with a molecular weight of approximately 307.24 g/mol. It is slightly soluble in water and has a high solubility in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards reducing agents and bases. It can undergo nitro reduction and methoxy substitution reactions.

1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol is typically synthesized via a multi-step process. The first step involves the synthesis of the indole core, followed by nitration and methylation reactions. Commonly used reagents include nitric acid and methanol. The final step involves coupling reactions to introduce the required substituents. This method ensures good yield and selectivity.

1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol is used in the pharmaceutical industry for the development of novel drug candidates. It also finds applications in the synthesis of organic dyes and pigments. Additionally, it is used in the field of materials science for the preparation of advanced polymers and sensors due to its unique chemical properties.

When handling 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Proper storage in a cool, dry place away from direct sunlight is essential. In case of spillage, use absorbent material and consult the safety data sheet (SDS) for specific cleanup procedures.