5-Bromo-2-chloro-3-fluoropyridine(CAS: 831203-13-5)

5-Bromo-2-chloro-3-fluoropyridine (CAS: 831203-13-5) is a crystalline solid with a molecular weight of approximately 246.01 g/mol. It has a low water solubility and is moderately soluble in common organic solvents such as ethanol and acetone. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents. It is often used in organic synthesis due to its ability to undergo substitution reactions.

5-Bromo-2-chloro-3-fluoropyridine (CAS: 831203-13-5) is commonly synthesized through a multistep process involving the introduction of bromine, chlorine, and fluorine functionalities onto pyridine. Typical methods include the use of bromination and chlorination of 3-fluoropyridine followed by further functionalization. Catalysts such as fuming sulfuric acid are often employed to control the reaction selectivity and yield.

5-Bromo-2-chloro-3-fluoropyridine (CAS: 831203-13-5) is used in various industries, particularly in pharmaceuticals and materials science. It serves as a key intermediate in the synthesis of more complex molecules and is also used in the development of sensors and semiconductors due to its unique chemical properties and reactivity.

When handling 5-Bromo-2-chloro-3-fluoropyridine (CAS: 831203-13-5), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or within a fume hood to minimize inhalation risks. Spills should be handled with appropriate absorbent materials and the area should be thoroughly cleaned. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.