1-(4-iodophenyl)-2,5-dimethyl-1H-pyrrole(CAS: 288608-09-3)

1-(4-Iodophenyl)-2,5-dimethyl-1H-pyrrole is a crystalline solid with a molecular weight of approximately 296.01 g/mol. It has a low solubility in water but is more soluble in organic solvents such as dichloromethane and tetrahydrofuran. This compound is known for its stability under normal conditions but can react with strong oxidizing agents. It shows minimal reactivity towards common bases and acids.

1-(4-Iodophenyl)-2,5-dimethyl-1H-pyrrole can be synthesized by first preparing 4-iodophenyl isocyanide, which is then reacted with 1,3-dimethyl-2-pyrrole. This reaction is typically carried out in the presence of a base such as triethylamine or pyridine to enhance the reaction yield. The process requires careful handling of iodine compounds to prevent hazardous reactions.

1-(4-Iodophenyl)-2,5-dimethyl-1H-pyrrole is primarily used in the pharmaceutical and chemical industries due to its unique chemical structure. It can be applied in the synthesis of various organic compounds, drug intermediates, and as a building block for developing new materials. Additionally, it has potential applications in the polymer and semiconductor industries for specialized applications.

When handling 1-(4-iodophenyl)-2,5-dimethyl-1H-pyrrole, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, well-ventilated area away from heat sources and oxidizing agents. Spills should be cleaned up carefully using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.