5-Hydroxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one(CAS: 80711-56-4)

5-Hydroxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one (CAS: 80711-56-4) is a crystalline solid with a molecular weight of approximately 210.22 g/mol. It has a solubility of about 0.01 g/L in water at 20°C. This compound is moderately reactive, particularly towards nucleophiles and electrophiles. It is not flammable but may undergo hydrolysis in basic conditions.

5-Hydroxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one (CAS: 80711-56-4) is commonly synthesized via a multi-step process involving the condensation of 3,3-dimethylindoline-2,3-dione with hydroxylation. Common catalysts include transition metals like palladium. The overall yield can range from 50-70%.

5-Hydroxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one (CAS: 80711-56-4) is used in the pharmaceutical industry for its potential as a precursor in the synthesis of bioactive compounds. It is also utilized in the polymer industry due to its structural rigidity and in the development of sensors and semiconductors for its electronic properties.

When handling 5-Hydroxy-3,3-dimethyl-1,3-dihydro-2H-indol-2-one (CAS: 80711-56-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.