2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine(CAS: 5466-43-3)

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is a white crystalline solid with a molecular weight of approximately 199.02 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong bases and reducing agents. This compound is known for its low solubility in water and high stability under normal conditions.

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine can be synthesized via a multistep reaction starting from 2,4-dichloropyrimidine. The key steps involve the addition of a dihydrocyclopentyl ring via a Wittig reaction followed by a reduction to form the final product. This process typically requires careful control of temperature and reagents to achieve high yield and selectivity.

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is primarily used in the pharmaceutical industry for the synthesis of certain antiviral drugs. It is also utilized in the polymer industry as a precursor for synthesizing various polymer materials and in the semiconductor industry for specific applications in electronic device manufacturing.

When handling 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate protocols, and the substance should be stored in a cool, dry place away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.