6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione(CAS: 13480-40-5)

6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione is a white to light yellow crystalline solid with a molecular weight of approximately 254.23 g/mol. It has a solubility of about 0.15 g/100 mL in water and is soluble in organic solvents like ethanol and acetone. It is known for its weak basicity and moderate reactivity, particularly in nucleophilic substitution reactions.

6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione is commonly synthesized through the condensation of 2-methylpyrazine with 5,8-dione using a mild base like potassium carbonate as a catalyst. The reaction typically yields 80-90% purity with good selectivity and high yield under mild conditions.

6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione finds applications in the pharmaceutical industry for its potential as a drug intermediate. It is also used in the synthesis of certain dyes and pigments. Additionally, it has potential uses in the development of sensors and semiconductors due to its unique electronic properties.

When handling 6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up promptly using appropriate absorbents, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.