2-Azaspiro[4.5]decan-1-one(CAS: 1005-85-2)

2-Azaspiro[4.5]decan-1-one (CAS: 1005-85-2) is a cyclic ketone with a molecular weight of approximately 168.24 g/mol. It has a crystalline form and is slightly soluble in water. The compound is moderately reactive, showing ketone reactivity and can undergo reactions such as reduction and condensation. It is insoluble in water but soluble in common organic solvents like ethanol and acetone.

2-Azaspiro[4.5]decan-1-one (CAS: 1005-85-2) is typically synthesized via a condensation reaction of an appropriately substituted acetaldehyde with a cyclic amine. Common methods involve the use of a Lewis acid catalyst, such as aluminum chloride, to promote the condensation. The yield can be up to 80%, with good selectivity for the azaspiro product.

2-Azaspiro[4.5]decan-1-one (CAS: 1005-85-2) is used in various industries. It finds applications in pharmaceuticals for the synthesis of certain drug candidates, in polymers as a precursor in polymerization reactions, and in sensors for detecting specific chemical or biological analytes. Additionally, it is used in the electronics industry for semiconductor applications.

When handling 2-Azaspiro[4.5]decan-1-one (CAS: 1005-85-2), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. Operations should be conducted in a well-ventilated area or a fume hood to minimize exposure to the vapor. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.