Ethyl 6-formyl-2-pyridinecarboxylate(CAS: 21908-10-1)

Ethyl 6-formyl-2-pyridinecarboxylate (CAS: 21908-10-1) is a crystalline compound with a molecular weight of approximately 180.18 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly under acidic conditions. It can undergo nucleophilic substitution and condensation reactions.

Ethyl 6-formyl-2-pyridinecarboxylate (CAS: 21908-10-1) can be synthesized via the condensation of formylacetate with 2-pyridinecarboxaldehyde. This reaction typically involves the use of a base like sodium hydroxide and is carried out in an organic solvent such as ethanol. The yield is generally around 75-85%, depending on the purity of the reactants and the reaction conditions.

Ethyl 6-formyl-2-pyridinecarboxylate (CAS: 21908-10-1) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has applications in the polymer industry for the modification of polymer properties and in the semiconductor industry for the production of organic semiconductors.

When handling Ethyl 6-formyl-2-pyridinecarboxylate (CAS: 21908-10-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up by wearing appropriate PPE, and the area should be thoroughly ventilated. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and safety measures.