1,4-Bis[(4-methylphenyl)sulfonyl]piperazine(CAS: 17046-84-3)

1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3) has a molecular weight of approximately 416.47 g/mol. It is a white crystalline solid with poor water solubility. The compound is reactive towards nucleophiles and can undergo sulfonamide formation. It is stable under normal conditions but should be handled with care to avoid moisture exposure.

1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3) can be synthesized through a multi-step process involving sulfonylation of piperazine with 4-methylbenzenesulfonyl chloride. Commonly used catalysts include phosphorus oxychloride, and the process proceeds with high selectivity, yielding a product with good purity.

1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3) is used in various industries, particularly in pharmaceuticals for its potential as a pharmaceutical intermediate. It is also utilized in polymers for its stable structure and in sensors due to its unique chemical properties. Its functionality in semiconductors is also being explored.

When handling 1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3), safety precautions include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The material should be stored in a closed container to prevent moisture absorption. Fume hood use is recommended during handling. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.