Ethyl (4-hydroxy-2-oxo-1-pyrrolidinyl)acetate(CAS: 62613-81-4)

Ethyl (4-hydroxy-2-oxo-1-pyrrolidinyl)acetate (CAS: 62613-81-4) is a colorless to pale yellow liquid with a molecular weight of approximately 170.24 g/mol. It is moderately soluble in water but highly soluble in organic solvents such as methanol and ethanol. This compound is known for its high reactivity, particularly in nucleophilic substitution reactions and esterification processes.

Ethyl (4-hydroxy-2-oxo-1-pyrrolidinyl)acetate (CAS: 62613-81-4) can be synthesized via the condensation of 2-oxo-1-pyrrolidinyl alcohol with ethyl acetate under acidic catalysis. The synthetic process typically involves refluxing the reactants in the presence of a Lewis acid catalyst like aluminum trichloride to achieve high yield and selectivity.

Ethyl (4-hydroxy-2-oxo-1-pyrrolidinyl)acetate (CAS: 62613-81-4) is used in pharmaceuticals for the synthesis of certain APIs and intermediates, as well as in the formulation of topical drugs. It is also utilized in the polymer industry for modifying properties of polymers and in the production of sensors and semiconductors for its reactivity and stability.

When handling Ethyl (4-hydroxy-2-oxo-1-pyrrolidinyl)acetate (CAS: 62613-81-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be handled carefully using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.