6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide(CAS: 720690-73-3)

6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide is a white to off-white solid with a molecular weight of approximately 450.47 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and dimethylformamide. This compound is reactive with bases and can undergo hydrolysis. It is stable under normal storage conditions but should be protected from moisture and light.

6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide is synthesized through multistep processes, typically involving the synthesis of the 2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl group, followed by coupling with 6-methylnicotinoyl chloride. Common catalysts and reagents include triethylamine and pyridine. The final step involves purification by recrystallization from ethanol or a suitable solvent mixture.

6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide is primarily used in the pharmaceutical industry for the development of potential therapeutic agents. It may also find applications in the sensor industry due to its unique chemical properties. Further research is ongoing to explore its potential in other fields such as polymers and materials science.

When handling 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.