4-(2-Methoxy-4-nitrophenyl)morpholine(CAS: 97459-72-8)

4-(2-Methoxy-4-nitrophenyl)morpholine is a crystalline compound with a molecular weight of approximately 271.14 g/mol. It is slightly soluble in water but has good solubility in organic solvents such as methanol and acetone. Chemically, it shows basic properties and is reactive towards acids, demonstrating moderate reactivity in nucleophilic substitution reactions.

4-(2-Methoxy-4-nitrophenyl)morpholine is typically synthesized through the reaction of 2-methoxy-4-nitrophenol with morpholine. The reaction is catalyzed by a strong base such as sodium hydride, leading to a good yield of the target compound with high selectivity. The reaction conditions are mild, and the product can be isolated by recrystallization.

4-(2-Methoxy-4-nitrophenyl)morpholine is used in various industries, including pharmaceuticals where it serves as an intermediate in the synthesis of drugs, and in the production of dyes and pigments. It also has applications in the polymer industry for producing functionalized polymers and in the development of sensors and semiconductors.

When handling 4-(2-Methoxy-4-nitrophenyl)morpholine, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that the work is conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.