Compound Q&A

How is 4-(2-Methoxy-4-nitrophenyl)morpholine (CAS: 97459-72-8) typically synthesized?

Answer

4-(2-Methoxy-4-nitrophenyl)morpholine
4-(2-Methoxy-4-nitrophenyl)morpholine is typically synthesized through the reaction of 2-methoxy-4-nitrophenol with morpholine. The reaction is catalyzed by a strong base such as sodium hydride, leading to a good yield of the target compound with high selectivity. The reaction conditions are mild, and the product can be isolated by recrystallization.

About

CAS No 97459-72-8
English Name 4-(2-Methoxy-4-nitrophenyl)morpholine
Molecular Formula C11H14N2O4
Molecular Weight 238.2399 g/mol
SMILES COC1=C(C=CC(=C1)[N+](=O)[O-])N2CCOCC2
InChIKey KORWLDQABONDQH-UHFFFAOYSA-N
Last Updated: 2026-01-13 06:10

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