Ethyl 1-(tert-butyl)-1H-1,2,3-triazole-4-carboxylate(CAS: 98013-35-5)

Ethyl 1-(tert-butyl)-1H-1,2,3-triazole-4-carboxylate is a crystalline solid with a molecular weight of approximately 238.27 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetone. Chemically, it is mildly reactive but stable under normal conditions. It exhibits acidity due to the carboxylate group.

Ethyl 1-(tert-butyl)-1H-1,2,3-triazole-4-carboxylate is synthesized by reacting tert-butyl 1H-1,2,3-triazole-4-carboxylate with ethylamine. The reaction is typically conducted in an inert atmosphere to prevent side reactions, and the product can be purified by recrystallization or column chromatography.

Ethyl 1-(tert-butyl)-1H-1,2,3-triazole-4-carboxylate is used in pharmaceuticals for the synthesis of certain drugs, as a precursor in polymer synthesis to enhance material properties, and in the development of chemical sensors due to its functional group reactivity.

When handling Ethyl 1-(tert-butyl)-1H-1,2,3-triazole-4-carboxylate, gloves and appropriate personal protective equipment (PPE) should be worn to protect against skin contact. Work should be carried out in a well-ventilated fume hood to avoid inhalation of fumes. Spills should be cleaned up using appropriate materials, and the compound should be stored in a cool, dry place away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information.