(11alpha)-11-Hydroxyandrost-4-ene-3,17-dione(CAS: 564-33-0)

(11alpha)-11-Hydroxyandrost-4-ene-3,17-dione is a steroid compound with a molecular weight of approximately 332.46 g/mol. It is a white, crystalline solid with a melting point around 145-147°C. This compound is poorly soluble in water but has good solubility in organic solvents such as methanol and ethanol. It is relatively stable under normal conditions but can react with strong acids or bases. It is used in various applications including pharmaceuticals and research due to its hormonal properties.

(11alpha)-11-Hydroxyandrost-4-ene-3,17-dione can be synthesized via the reduction of androst-4-ene-3,17-dione, followed by selective hydroxylation at position 11. This process typically involves the use of a hydrogenation catalyst such as palladium on carbon under hydrogen gas pressure. The hydroxylation step is often catalyzed by specific enzymes or chemical reagents to achieve high selectivity and yield.

(11alpha)-11-Hydroxyandrost-4-ene-3,17-dione is primarily used in the pharmaceutical industry for the production of hormonal drugs. It is also utilized in research and development for its hormonal properties. Additionally, it has some applications in the cosmetics industry for its potential skin-related benefits. Its specific use in the polymer and semiconductor industries is limited but may be explored for specialized applications.

When handling (11alpha)-11-Hydroxyandrost-4-ene-3,17-dione, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. Use a fume hood for any handling or preparation to minimize exposure. In case of a spill, it is recommended to use appropriate spill cleanup materials and refer to the Safety Data Sheet (SDS) for specific instructions. Accidental ingestion or skin contact should be treated immediately with water rinse and medical attention if necessary.