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1-(tert-Butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole(CAS: 1148004-02-7)

1-(tert-Butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
CAS Number

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Basic Information

Molecular Formula
C20H31BFNO2Si
Molecular Weight
375.37 g/mol

Chemical Identifiers

SMILES
B1(OC(C(O1)(C)C)(C)C)C2=C(C=CC3=C2C=CN3[Si](C)(C)C(C)(C)C)F
InChIKey
OAMAAQPCABOWNH-UHFFFAOYSA-N

Database References

MDL Number
MFCD22690780

FAQ

This compound is a solid with a crystalline form. Its molecular weight is approximately 524.5 g/mol. It has limited water solubility and is moderately soluble in organic solvents like DMSO and THF. Reactivity is moderate, with selective reactivity towards boronic acids and fluorous groups. It is stable under standard laboratory conditions.
The compound is typically synthesized using a variety of methods, including boronate ester formation with a fluorous group. Commonly, palladium catalysts are used for cross-coupling reactions. The overall yield is moderate to good, depending on the specific reaction conditions and purity of the starting materials.
This compound is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds. It also has potential applications in the polymer industry for developing new materials, and in the semiconductor industry for electronic applications. Its use in sensors is also promising due to its unique chemical properties.
Handling this compound requires appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be done in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed guidelines on handling and storage.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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