5-[3,5-bis(3,5-dicarboxyphenyl)-2,4,6-trimethyl-phenyl]benzene-1,3-dicarboxylic acid(CAS: 1374764-27-8)

5-[3,5-bis(3,5-dicarboxyphenyl)-2,4,6-trimethyl-phenyl]benzene-1,3-dicarboxylic acid is a crystalline solid with a high molecular weight due to its complex structure. It has a low solubility in water but is more soluble in organic solvents. The compound is known for its high reactivity, particularly in esterification and amide formation reactions. Its stability and reactivity make it useful in various chemical processes.

5-[3,5-bis(3,5-dicarboxyphenyl)-2,4,6-trimethyl-phenyl]benzene-1,3-dicarboxylic acid is synthesized through a multi-step process involving the condensation of 4,6-bis(3,5-dicarboxyphenyl)-2,4,6-trimethylphenylacetic acid and benzene-1,3-dicarboxylic anhydride. Common catalysts include strong acids like sulfuric acid. The process typically yields a high purity product with good selectivity and yield.

5-[3,5-bis(3,5-dicarboxyphenyl)-2,4,6-trimethyl-phenyl]benzene-1,3-dicarboxylic acid finds applications in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients, in the polymer industry for developing new polymeric materials, and in the electronics industry for use in sensor and semiconductor fabrication.

When handling 5-[3,5-bis(3,5-dicarboxyphenyl)-2,4,6-trimethyl-phenyl]benzene-1,3-dicarboxylic acid, it is essential to use proper personal protective equipment (PPE) such as gloves and lab coats. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate solvent and waste should be disposed of according to local regulations. Safety data sheets (SDS) should be consulted for detailed safety information.