2-Oleoylglycerol(CAS: 3443-84-3)

2-Oleoylglycerol is a clear, colorless to slightly yellow liquid. It has a molecular weight of approximately 328.45 g/mol. Its solubility in water is low, but it is highly soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable under neutral and slightly basic conditions but can undergo hydrolysis under acidic conditions. It does not readily react with common oxidizers and is stable to light and air.

2-Oleoylglycerol can be synthesized via the condensation of glycerol with oleic acid in the presence of a catalyst such as sodium hydroxide or potassium hydroxide. The reaction typically occurs in an aqueous phase and requires careful control of pH and temperature to achieve high selectivity and yield. The product can be purified by recrystallization or by precipitation followed by filtration and drying.

2-Oleoylglycerol is used in the pharmaceutical industry for its potential as a gastrointestinal prodrug. It is also utilized in the food industry as an emulsifier and in the cosmetic industry for its moisturizing properties. Additionally, it has applications in sensors and semiconductors due to its amphiphilic nature, which makes it useful in creating stable dispersions and films.

When handling 2-Oleoylglycerol, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from sources of heat and light. If a spill occurs, it should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed emergency response procedures and storage guidelines.