3-Bromo-4-chloro-1H-indazole(CAS: 885521-40-4)

3-Bromo-4-chloro-1H-indazole is a crystalline solid with a molecular weight of 220.02 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound has moderate reactivity, particularly towards nucleophiles and reducing agents. It is prone to substitution reactions under certain conditions.

3-Bromo-4-chloro-1H-indazole can be synthesized via the condensation of 4-chloro-1H-indazole with bromine in an appropriate solvent such as chloroform. The reaction is catalyzed by a base like sodium carbonate and proceeds with good selectivity and yield under mild conditions.

3-Bromo-4-chloro-1H-indazole finds applications in pharmaceuticals, where it serves as an intermediate for the synthesis of various drugs. It also has uses in the production of certain dyes and pigments, and can be utilized in the development of sensors and other materials in the polymer industry.

When handling 3-Bromo-4-chloro-1H-indazole, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a fume hood and away from reducing agents and strong bases. In case of a spill, it is necessary to clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.