4-Methoxy-1,3-benzothiazol-2(3H)-one(CAS: 80567-66-4)

4-Methoxy-1,3-benzothiazol-2(3H)-one is a crystalline compound with a molecular weight of approximately 243.26 g/mol. It has low water solubility and good solubility in organic solvents. This compound is known for its stability and low reactivity under normal conditions, but can undergo hydrolysis in the presence of strong acids or bases.

4-Methoxy-1,3-benzothiazol-2(3H)-one can be synthesized via the condensation of benzothiazole and methanol in the presence of a suitable catalyst. Common methods include using acetic acid or p-toluenesulfonic acid as a catalyst, with a yield of around 80-90%. The reaction is typically carried out under mild conditions to ensure high selectivity.

4-Methoxy-1,3-benzothiazol-2(3H)-one is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the polymer industry for the development of new materials, and in the sensor industry for its sensing capabilities. Additionally, it can be used in the semiconductor industry as a cleaning agent.

When handling 4-Methoxy-1,3-benzothiazol-2(3H)-one, appropriate personal protective equipment (PPE) should be used, including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be carefully cleaned up using appropriate methods, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for specific safety information and guidelines.