4-Fluoro-3-(trifluoromethyl)benzaldehyde(CAS: 67515-60-0)

4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0) is a white crystalline solid with a molecular weight of 252.12 g/mol. It has a melting point of 59-61°C and is slightly soluble in water. This compound is highly reactive due to the presence of the aldehyde group and fluorine substituents, making it an active molecule in organic synthesis.

4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0) can be synthesized via the reaction of 3-(trifluoromethyl)benzaldehyde with fluoride sources such as tetrabutylammonium fluoride (TBAF). The reaction is carried out under anhydrous conditions to enhance yield and selectivity. The use of catalysts like palladium complexes can improve the reaction efficiency and minimize side products.

4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0) is primarily used in the pharmaceutical industry for the synthesis of various drug intermediates. It also finds applications in the polymer industry for the development of novel materials, in sensor technology for detecting specific gases, and in semiconductor manufacturing for etching processes.

When handling 4-Fluoro-3-(trifluoromethyl)benzaldehyde (CAS: 67515-60-0), it is essential to wear personal protective equipment such as gloves, goggles, and a lab coat. Ensure the use of a fume hood to avoid inhalation of vapors. Spills should be cleaned up with caution using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.