3-Chloroisoquinolin-4-OL(CAS: 101774-33-8)

3-Chloroisoquinolin-4-ol (CAS: 101774-33-8) is a white crystalline solid with a molecular weight of 202.59 g/mol. It has a solubility of 0.03 g/L in water and is slightly soluble in ethanol. It is moderately reactive with bases and oxidizing agents. This compound is used in various organic synthesis reactions and as an intermediate in the pharmaceutical industry.

3-Chloroisoquinolin-4-ol (CAS: 101774-33-8) can be synthesized by the reduction of 3-chloroisochinoline-4-one with a reducing agent like sodium borohydride in an alcohol solvent. The reaction is typically carried out at room temperature and provides a yield of around 70-80%. This method involves the use of hazardous chemicals, so proper safety precautions are necessary.

3-Chloroisoquinolin-4-ol (CAS: 101774-33-8) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various bioactive compounds. It is also used in the development of new drugs and in the production of certain polymers and sensors.

When handling 3-Chloroisoquinolin-4-ol (CAS: 101774-33-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and waste should be disposed of in accordance with local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.