3-Pyridinecarbothioamide(CAS: 4621-66-3)

3-Pyridinecarbothioamide (CAS: 4621-66-3) is a white crystalline solid with a molecular weight of approximately 140.17 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it is reactive, particularly towards nucleophiles and oxidizing agents, making it useful in various organic synthesis reactions.

3-Pyridinecarbothioamide (CAS: 4621-66-3) is typically synthesized via the reaction of 3-pyridyl isothiocyanate with primary amines. This reaction is often catalyzed by Lewis acids or metal complexes, leading to a high yield of the desired product with good selectivity.

3-Pyridinecarbothioamide (CAS: 4621-66-3) finds applications in the pharmaceutical industry as a precursor for drug synthesis, particularly in the development of antiviral and anticancer drugs. It is also used in the polymer industry for the modification of polymer properties and in the sensing industry for the development of gas sensors.

When handling 3-Pyridinecarbothioamide (CAS: 4621-66-3), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of spillage, neutralize with an acid or base and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.