2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol(CAS: 35836-73-8)

2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol is a colorless to slightly yellow oil with a molecular weight of approximately 178.28 g/mol. It has a low melting point of -38°C and a boiling point of around 160°C. The compound is slightly soluble in water but miscible with common organic solvents. It is reactive towards strong acids and bases, making it susceptible to hydrolysis.

2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol is synthesized through a multi-step process involving the synthesis of the bicyclic ketone followed by its reduction to the alcohol. Common methods include the Wittig reaction, Grignard reagent addition, or catalytic hydrogenation. The overall yield is around 70-80%, with high selectivity towards the desired product.

2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol finds applications in pharmaceuticals for its potential role as a precursor in drug synthesis, in polymer manufacturing for modifying properties of polymers, and in the development of sensors and semiconductors due to its unique structural features.

When handling 2-[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]ethan-1-ol, proper personal protective equipment (PPE) is necessary, including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from strong acids and bases. Fume hoods should be used during handling to minimize inhalation risks. In case of accidental spill, neutralize with a suitable base, then clean up with absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed safety information.