1-{1-[(4-Methyl-1-piperazinyl)methyl]cyclopropyl}methanamine(CAS: 1015846-52-2)

1-{1-[(4-Methyl-1-piperazinyl)methyl]cyclopropyl}methanamine is a crystalline solid with a molecular weight of approximately 247.33 g/mol. It has a pKa of 8.5 and is moderately soluble in water. The compound exhibits good reactivity towards nucleophiles and can undergo substitution reactions. It is stable under normal storage conditions but requires protection from moisture and air.

1-{1-[(4-Methyl-1-piperazinyl)methyl]cyclopropyl}methanamine can be synthesized via an amination reaction of cyclopropylmethylamine with 4-methylpiperazine. The reaction is typically carried out in the presence of a base such as triethylamine and yields up to 85% purity. The process is selective and efficient, making it suitable for large-scale production.

1-{1-[(4-Methyl-1-piperazinyl)methyl]cyclopropyl}methanamine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain bioactive compounds. It is also utilized in the development of sensors and as a building block in the production of polymers with specific properties.

When handling 1-{1-[(4-Methyl-1-piperazinyl)methyl]cyclopropyl}methanamine, wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, follow the safety data sheet (SDS) guidelines for cleanup and disposal.