cis-4-Methylcyclohexanol(CAS: 7731-28-4)

cis-4-Methylcyclohexanol is a colorless liquid with a molecular weight of approximately 114.19 g/mol. It has a pungent odor and a specific gravity of 0.906. This compound is slightly soluble in water but miscible with most organic solvents. It is mildly reactive towards oxidizing agents and acidic conditions. Its boiling point is 182°C and melting point is -14°C.

cis-4-Methylcyclohexanol can be synthesized via reduction of 4-methylcyclohexanone using hydrogen gas in the presence of a catalyst like palladium on carbon. Another method involves the Wittig olefination of methyltriphenylphosphonium bromide with propargyl alcohol, followed by hydrogenation. High selectivity and good yields are typically achieved.

cis-4-Methylcyclohexanol is primarily used in the fragrance and perfume industry as a flavor and fragrance ingredient. It is also utilized in the pharmaceutical industry as a precursor for the synthesis of other molecules. Additionally, it has applications in the polymer industry as a plasticizer and in the production of coatings and adhesives.

cis-4-Methylcyclohexanol should be handled in a well-ventilated area with appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from strong oxidizers and acids. In case of a spill, it should be cleaned up with appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed emergency procedures and handling instructions.