2-Chloro-N-(2-oxotetrahydro-3-thiophenyl)acetamide(CAS: 84611-22-3)

2-Chloro-N-(2-oxotetrahydro-3-thiophenyl)acetamide (CAS: 84611-22-3) is a crystalline solid with a molecular weight of approximately 221.66 g/mol. It is slightly soluble in water and has a high solubility in organic solvents like dichloromethane and acetonitrile. The compound is reactive towards nucleophiles and can undergo substitution reactions. It has a pKa of around 6.5.

2-Chloro-N-(2-oxotetrahydro-3-thiophenyl)acetamide (CAS: 84611-22-3) is typically synthesized via a multi-step process starting from 2-chloroacetamide and 3-thiophenecarboxaldehyde. The key steps involve condensation followed by ring closure to form the thienyl moiety. The reaction is usually catalyzed by a Lewis acid and proceeds with good selectivity and yield.

2-Chloro-N-(2-oxotetrahydro-3-thiophenyl)acetamide (CAS: 84611-22-3) is used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also employed in the polymer industry for the development of novel materials with specific thermal and mechanical properties. Additionally, it finds applications in the production of sensors and semiconductors due to its functional groups.

When handling 2-Chloro-N-(2-oxotetrahydro-3-thiophenyl)acetamide (CAS: 84611-22-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.