1-Cyclohexyl-2,4(1H,3H)-pyrimidinedione(CAS: 712-43-6)

1-Cyclohexyl-2,4(1H,3H)-pyrimidinedione is a white crystalline solid with a molecular weight of approximately 228.21 g/mol. It is sparingly soluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is fairly stable under normal conditions but can react with strong acids and bases. It has a melting point of around 160-163°C.

1-Cyclohexyl-2,4(1H,3H)-pyrimidinedione is usually synthesized through a condensation reaction between cyclohexylamine and acetic anhydride. The reaction is catalyzed by a weak acid such as acetic acid and proceeds under heating conditions. The yield is generally around 75-80%, and the product can be purified by recrystallization.

1-Cyclohexyl-2,4(1H,3H)-pyrimidinedione is used in pharmaceuticals, particularly as a precursor in the synthesis of drug intermediates. It is also utilized in the production of certain polymers and as a component in sensors and semiconductors due to its unique chemical properties.

When handling 1-Cyclohexyl-2,4(1H,3H)-pyrimidinedione, ensure to maintain proper ventilation and use a fume hood. Wear appropriate personal protective equipment such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and heat sources. In case of spills, immediately clean up using appropriate absorbents, and consult the Safety Data Sheet (SDS) for further instructions.