4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol(CAS: 98198-24-4)

4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol (CAS: 98198-24-4) is a crystalline solid with a molecular weight of approximately 249.27 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and methanol. This compound is known for its reactivity due to the presence of the amino and thiol functional groups, which can participate in various chemical reactions such as nucleophilic substitution and condensation reactions.

4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol is typically synthesized via the condensation of 2-thiouracil and an amino derivative. The reaction usually involves the use of a mild base such as sodium bicarbonate as a catalyst. The yield is generally around 70-80%, and the product can be purified by recrystallization or column chromatography.

4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol (CAS: 98198-24-4) is widely used in the pharmaceutical industry for its potential as a drug candidate. It also finds applications in the semiconductor industry for its use in organic electronics and sensors. Additionally, it has potential uses in the polymer industry for the development of new materials.

When handling 4-Amino-7H-pyrrolo[2,3-d]pyrimidine-2-thiol (CAS: 98198-24-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. This compound should be used in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly washed. Refer to the Material Safety Data Sheet (MSDS) for detailed handling and disposal instructions.