2-Methyl-2-propanyl 5,7-dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate(CAS: 851784-76-4)

2-Methyl-2-propanyl 5,7-dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate is a solid with a crystalline form. Its molecular weight is approximately 331.04 g/mol. The compound has low solubility in water but is soluble in organic solvents like ethanol and acetonitrile. It is moderately reactive and can undergo nucleophilic substitution reactions and ester hydrolysis.

2-Methyl-2-proanyl 5,7-dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate is synthesized via a multi-step process. Commonly, it involves the condensation of 5,7-dichloro-6-hydroxy-2(1H)-isoquinolinecarboxylic acid with 2-methyl-2-propanol, catalyzed by an acid catalyst such as sulfuric acid. The reaction yields a high purity product with good selectivity and high yield.

2-Methyl-2-proanyl 5,7-dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate is used in the pharmaceutical industry for the synthesis of certain drugs. It may also be used in the polymer industry as a reactive monomer, in the semiconductor industry for its photochemical properties, and in sensor technology for its detection capabilities.

When handling 2-Methyl-2-proanyl 5,7-dichloro-6-hydroxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation of vapors. In case of spill, immediately clean up the area using appropriate absorbent materials and follow the manufacturer’s safety data sheet (SDS) guidelines for further disposal and cleanup procedures.