2-[(2-Nitrophenyl)amino]ethanol(CAS: 4926-55-0)

2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0) is a crystalline solid with a molecular weight of approximately 222.13 g/mol. It has a pKa around 5.5 and is moderately soluble in water. This compound is relatively reactive, especially towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place to prevent hydrolysis.

2-[(2-Nitrophenyl)amino]ethanol is commonly synthesized via the reaction of 2-nitrophenol with ethanol in the presence of a base such as sodium hydroxide. The process typically involves heating the mixture to reflux, followed by workup and purification steps. High selectivity and good yield are achievable with this method.

2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0) is used in the pharmaceutical industry for synthesizing various compounds. It is also employed in the production of dyes, organic semiconductors, and as a precursor in polymer synthesis. Its application in sensors and as a reagent in analytical chemistry is also notable.

When handling 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of spills, immediately clean up with appropriate absorbent materials and wash the area with water. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.