1-Bromo-8-chlorodibenzo[b,d]furan(CAS: 2173554-83-9)

1-Bromo-8-chlorodibenzo[b,d]furan is a crystalline solid with a molecular weight of approximately 274.03 g/mol. It has low water solubility and is soluble in organic solvents like dichloromethane and acetonitrile. This compound is reactive, particularly towards nucleophilic substitution reactions. It is not flammable but is corrosive to some metals.

1-Bromo-8-chlorodibenzo[b,d]furan is typically synthesized via electrophilic aromatic substitution reactions. The reaction involves bromination of 8-chlorodibenzo[b,d]furan followed by bromination at the 1-position. Common catalysts include Lewis acids such as aluminum bromide. The overall yield is moderate, around 50-70%, and the reaction is selective for the 1-position bromination.

1-Bromo-8-chlorodibenzo[b,d]furan is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the development of functional polymers. Additionally, it is utilized in the manufacturing of sensors and in the semiconductor industry for specific material modifications.

When handling 1-Bromo-8-chlorodibenzo[b,d]furan, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood. Spills should be cleaned up with care using absorbent materials, and the area should be thoroughly rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.