Diethyl (4-bromobenzyl)malonate(CAS: 70146-78-0)

Diethyl (4-bromobenzyl)malonate (CAS: 70146-78-0) is a crystalline solid with a molecular weight of approximately 296.05 g/mol. It has a high solubility in organic solvents such as ethanol and acetone but is insoluble in water. Chemically, it is moderately reactive and can undergo ester hydrolysis, bromination, and other substitution reactions under appropriate conditions.

Diethyl (4-bromobenzyl)malonate is typically synthesized via the reaction of 4-bromobenzaldehyde with malonic acid in the presence of an acid catalyst, such as sulfuric acid. The reaction yields a mixture of isomers, and purification steps including recrystallization are often required to obtain high purity product.

Diethyl (4-bromobenzyl)malonate (CAS: 70146-78-0) is used in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry for modifying material properties. It also finds applications in sensor technology and semiconductor manufacturing, where its bromine functionality is utilized for functionalization purposes.

When handling Diethyl (4-bromobenzyl)malonate (CAS: 70146-78-0), it is important to wear appropriate personal protective equipment (PPE), such as gloves and goggles. Work should be performed in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always refer to the safety data sheet (SDS) for detailed handling and safety information.