3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid(CAS: 797755-11-4)

3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid has a crystalline form with a molecular weight of approximately 412.48 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound is reactive towards nucleophilic substitution and has moderate reactivity with common reagents. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid is typically synthesized through palladium-catalyzed cross-coupling reactions. The key steps involve the activation of aryl boronic acid derivatives with a palladium catalyst, followed by coupling with a bromo or iodo aromatic compound. The reaction is selective and yields a high percentage of the desired product.

3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid is used in the pharmaceutical industry for the synthesis of various drug molecules. It also finds applications in polymer chemistry for the modification of polymer structures and in sensor technology for developing chemical sensors. Additionally, it is used in semiconductor manufacturing for surface modifications.

When handling 3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a fume hood and handled in a well-ventilated area. In case of spill, immediately clean up the area under proper safety guidelines and consult the Safety Data Sheet (SDS) for specific spill procedures.