O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)methyl)hydroxylamine(CAS: 628703-61-7)

O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)methyl)hydroxylamine has a crystalline form and a molecular weight of approximately 335.37 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is also known to exhibit good stability under normal conditions.

O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)methyl)hydroxylamine is typically synthesized by the reaction of 3-(methylaminomethyl)pyridin-6-yl) hydrazide with 1H-pyrazole-1-carbaldehyde under basic conditions. The reaction involves the condensation of these two reagents to form the desired product with good selectivity and yield, usually achieved in an organic solvent like dimethylformamide (DMF).

O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)methyl)hydroxylamine finds applications in the pharmaceutical industry due to its bioactive properties. It is also used in the synthesis of other compounds for polymer applications and as a sensor material in chemical sensing devices. Its use in semiconductors is less common but not entirely absent, where it may serve as a precursor or intermediate.

When handling O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)methyl)hydroxylamine, it is essential to wear appropriate personal protective equipment (PPE), such as gloves and safety glasses. Work should be conducted in a well-ventilated area or a fume hood. In the event of a spill, it should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always consult the Safety Data Sheet (SDS) for more detailed handling instructions.