(3-Methylpyridin-4-yl)methanamine(CAS: 97004-05-2)

(3-Methylpyridin-4-yl)methanamine is a colorless liquid with a molecular weight of approximately 157.21 g/mol. It has a pKa of around 6.8 and is partially soluble in water. This compound is reactive towards basic conditions and can undergo nucleophilic substitution reactions.

(3-Methylpyridin-4-yl)methanamine can be synthesized via the reduction of 3-methylpyridine-4-carbaldehyde with sodium borohydride in methanol. The process yields a 70-75% conversion with good selectivity, and the reaction is performed under mild conditions.

(3-Methylpyridin-4-yl)methanamine finds applications in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for the modification of polymer properties. It is also used in the production of sensors and as a ligand in coordination chemistry.

(3-Methylpyridin-4-yl)methanamine should be handled in a well-ventilated area or a fume hood. Use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Spills should be cleaned up using absorbent materials, and the area should be flushed with water. Consult the Safety Data Sheet (SDS) for detailed handling instructions.