N,N-Diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline(CAS: 267221-88-5)

N,N-Diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 267221-88-5) is a white crystalline solid with a molecular weight of approximately 478.5 g/mol. It is sparingly soluble in water but soluble in common organic solvents like ethanol and dichloromethane. The compound exhibits moderate reactivity, particularly in the presence of moisture, and is stable under normal conditions but should be handled under inert conditions to avoid decomposition.

N,N-Diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is typically synthesized via a multistep reaction involving the coupling of phenyl boronic acid with 4-aminophenyl boronic acid. The reaction is facilitated by a palladium catalyst, such as Pd(PPh3)4, in the presence of a base like sodium carbonate. The process yields a product with high selectivity and a good yield, making it suitable for industrial applications.

N,N-Diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 267221-88-5) has applications in the pharmaceutical industry, particularly in the synthesis of drug intermediates. It is also used in the polymer industry for preparing advanced materials, and in the sensor and semiconductor industries for its unique electronic properties. Its use in these industries highlights its importance in modern chemical synthesis and material science.

When handling N,N-Diphenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 267221-88-5), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid exposure to air moisture. In case of a spill, it should be cleaned up with caution using appropriate absorbents, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.