(S)-1-Phenylethanesulfonic Acid(CAS: 86963-38-4)

(S)-1-Phenylethanesulfonic Acid has a crystalline form, with a molecular weight of approximately 168.23 g/mol. It is slightly soluble in water and soluble in organic solvents. Chemically, it reacts readily with bases and has a pKa of about 1.7.

(S)-1-Phenylethanesulfonic Acid is commonly synthesized through the sulfonation of 1-phenylethanol using sulfur trioxide. The reaction is conducted under acidic conditions, and typical yields range from 70% to 85%. High selectivity for the (S) enantiomer is achieved using chiral catalysts.

(S)-1-Phenylethanesulfonic Acid finds applications in pharmaceuticals, where it is used as an intermediate in the synthesis of chiral drugs. It is also utilized in the production of certain polymers and in the development of sensors and semiconductors.

When handling (S)-1-Phenylethanesulfonic Acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to prevent inhalation. In the event of a spill, use appropriate spill cleanup materials and refer to the safety data sheet (SDS) for detailed instructions.