[5-(1-Propyn-1-yl)-3-pyridinyl]boronic acid(CAS: 917471-30-8)

The compound [5-(1-Propyn-1-yl)-3-pyridinyl]boronic acid has a crystalline form and a molecular weight of approximately 232.27 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetonitrile. The compound shows moderate reactivity in boronic acid reactions, making it useful in a variety of organic synthesis applications.

[5-(1-Propyn-1-yl)-3-pyridinyl]boronic acid is commonly synthesized via the reaction of 3-bromopyridine with 1-propynylboronic acid in the presence of a catalyst such as Pd(PPh3)4. The reaction typically yields a high purity product with a high selectivity, and the reaction conditions can be optimized for specific applications in organic synthesis.

[5-(1-Propyn-1-yl)-3-pyridinyl]boronic acid is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various complex molecules and is also utilized in the development of materials for sensors and semiconductors.

When handling [5-(1-Propyn-1-yl)-3-pyridinyl]boronic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and used in a fume hood to minimize exposure. In case of spillage, follow the manufacturer's safety data sheet (SDS) for proper cleanup procedures.