1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine(CAS: 26662-94-2)

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine is a phospholipid with a molecular weight of approximately 750 Da. It is slightly soluble in water and organic solvents. This compound can undergo hydrolysis under acidic or basic conditions and can form hydrogen bonds with other molecules. It typically exists as a white to off-white crystalline powder at room temperature.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine can be synthesized via a condensation reaction between palmitoyl and oleoyl groups with 1-ethanolamine, followed by phosphorylation. Commonly, this is achieved using catalytic amounts of phosphoric acid and can yield up to 95% of the target compound, with good selectivity.

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine is utilized in pharmaceuticals for its role in drug delivery systems and as a stabilizer. It is also used in the polymer industry for improving the biocompatibility of polymers and in the development of biosensors. Additionally, it finds applications in semiconductor technology for surface modification.

When handling 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, ensure proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be handled under a chemical fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed safety information and disposal procedures.