N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline(CAS: 330792-75-1)

N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 330792-75-1) is a white crystalline solid with a molecular weight of approximately 341.33 g/mol. It has a high solubility in organic solvents such as dimethylformamide and acetonitrile but is poorly soluble in water. The compound is reactive towards nucleophiles and exhibits good stability in neutral and acidic conditions.

N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 330792-75-1) can be synthesized by the boronate esterification of an aniline with a boronic acid, typically using a palladium catalyst and a base such as cesium carbonate. The reaction is carried out in an organic solvent and yields the target compound with high selectivity and good yield.

N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 330792-75-1) is primarily used in pharmaceuticals and materials science. It serves as a key intermediate in the synthesis of various pharmaceuticals and as a building block for functional polymers and organic semiconductors.

When handling N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 330792-75-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be handled in a fume hood to minimize exposure. In the event of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always consult the SDS for detailed handling and safety information.