Ethyl 4-amino-3-chlorobenzoate(CAS: 82765-44-4)

Ethyl 4-amino-3-chlorobenzoate (CAS: 82765-44-4) is a white to off-white crystalline solid with a molecular weight of approximately 226.61 g/mol. It has a solubility of about 0.14 g/100 mL in water and is more soluble in organic solvents like ethanol. Chemically, it is relatively stable but may react with strong acids or bases. It is insoluble in water but soluble in organic solvents, making it useful in various applications.

Ethyl 4-amino-3-chlorobenzoate (CAS: 82765-44-4) is typically synthesized via the reaction of 4-amino-3-chlorobenzoic acid with ethyl chloroformate in the presence of a base like sodium hydroxide. The yield is around 85%, and the reaction is selective, producing the desired product with minimal by-products. The process is efficient and can be scaled up for industrial use.

Ethyl 4-amino-3-chlorobenzoate (CAS: 82765-44-4) is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It also finds applications in the polymer industry for the production of specific polymers and in the electronics industry for components in sensors and semiconductors. Its versatility makes it valuable in multiple sectors.

When handling Ethyl 4-amino-3-chlorobenzoate (CAS: 82765-44-4), ensure proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight and flammable materials. Use a fume hood during handling to avoid inhalation of vapors. In case of a spill, clean up with appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.