(6-Fluoro-1H-indol-3-yl)acetonitrile(CAS: 2341-25-5)

(6-Fluoro-1H-indol-3-yl)acetonitrile is a colorless to white crystalline solid with a molecular weight of approximately 215.14 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetone. This compound is relatively stable under normal conditions but can react with strong acids and bases. It is typically used in organic synthesis and pharmaceuticals.

(6-Fluoro-1H-indol-3-yl)acetonitrile is commonly synthesized via the reaction of 6-fluoroindole with hydrogen cyanide in the presence of a base like sodium hydroxide. This method provides high selectivity and good yield, making it a preferred route for industrial production.

(6-Fluoro-1H-indol-3-yl)acetonitrile is primarily used in the pharmaceutical industry for developing new drug candidates. It is also used in the synthesis of certain polymers and sensors due to its structural properties. Additionally, it has applications in organic electronics, particularly in the fabrication of organic semiconductors.

When handling (6-Fluoro-1H-indol-3-yl)acetonitrile, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be stored in a cool, dry place away from heat and ignition sources. In case of a spill, it should be cleaned up using appropriate procedures as outlined in the Material Safety Data Sheet (MSDS/SDS). Fume hoods should be used during handling to minimize inhalation risk.