1-(bromomethyl)-2-iodobenzene(CAS: 40400-13-3)

1-(bromomethyl)-2-iodobenzene is a solid at room temperature. Its molecular weight is approximately 326.01 g/mol. This compound is poorly soluble in water but soluble in organic solvents like chloroform and acetone. It is reactive towards nucleophiles and can undergo substitution reactions.

1-(bromomethyl)-2-iodobenzene can be synthesized by reacting 2-iodobenzyl bromide with benzene. The reaction typically involves refluxing under anhydrous conditions. The yield is moderate, and the reaction is selective for the desired product.

1-(bromomethyl)-2-iodobenzene finds applications in pharmaceuticals and organic synthesis. It is used as an intermediate in the synthesis of certain drug molecules and in academic research for studying organic reactions.

When handling 1-(bromomethyl)-2-iodobenzene, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up according to standard laboratory procedures, and the material safety data sheet (MSDS) should be consulted for specific handling instructions.