2-Bromo-4-nitroaniline(CAS: 13296-94-1)

2-Bromo-4-nitroaniline is a crystalline solid with a molecular weight of approximately 227.03 g/mol. It has a melting point of around 220-222°C and a boiling point of around 315°C. It is slightly soluble in water but more soluble in organic solvents like ethanol. Chemically, it is stable under normal conditions but can react with reducing agents and strong bases. It is used as an intermediate in the synthesis of dyes and pharmaceuticals.

2-Bromo-4-nitroaniline is typically synthesized by bromination of 4-nitroaniline using N-bromosuccinimide (NBS) as the brominating agent. The reaction is typically carried out in the presence of a radical initiator such as azobisisobutyronitrile (AIBN) to improve the yield and selectivity. The reaction is performed under mild conditions to avoid side reactions.

2-Bromo-4-nitroaniline is used in the pharmaceutical industry as an intermediate for the synthesis of various drug compounds. It is also used in the dye industry to produce specific types of dyes. Additionally, it has applications in the research of sensors and semiconductors.

When handling 2-Bromo-4-nitroaniline, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate materials such as sodium bisulfite to neutralize the acid. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.