(4-Bromo-2-methoxyphenyl)acetonitrile(CAS: 858523-37-2)

(4-Bromo-2-methoxyphenyl)acetonitrile (CAS: 858523-37-2) is a white to off-white crystalline solid with a molecular weight of approximately 264.06 g/mol. It is only slightly soluble in water but soluble in organic solvents like ethanol and acetone. It is moderately reactive and can undergo nucleophilic substitution and electrophilic aromatic substitution reactions. It is typically stored in a cool, dry place away from moisture and light.

(4-Bromo-2-methoxyphenyl)acetonitrile (CAS: 858523-37-2) can be synthesized via a bromination reaction of 2-methoxyphenylacetonitrile followed by a dehydrobromination step. The synthesis involves the use of a brominating agent like N-bromosuccinimide (NBS) and a catalyst like ferric bromide. The yield is typically around 70-80%, depending on the reaction conditions and purification methods.

(4-Bromo-2-methoxyphenyl)acetonitrile (CAS: 858523-37-2) is primarily used in pharmaceuticals for the synthesis of drug intermediates. It is also used in the polymer industry as a monomer or additive. Additionally, it has potential applications in the development of sensors and semiconductors due to its functional groups that can participate in various chemical reactions.

When handling (4-Bromo-2-methoxyphenyl)acetonitrile (CAS: 858523-37-2), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood due to its reactivity. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and storage procedures.